I've been shooting a 6.5 creed for 6 years. I've harvested 1 antelope and 2 deer with it. All 3 with different bullets.
I shot my antelope at 480 yards with the Berger 140 vld hunting bullet. I shot him 3 times twice in the chest and once through both legs. All 3 of the bullets penciled through doing very little damage.
One deer I shot at 430 yards died with one shot but I was not impressed with the barnes 127 grain bullet.
Another deer I shot at 300 yards with the 143 eldx. I shot this deer through both shoulders the bullet stayed intact and was in the skin on the other side of the animal.
I believe that bullet selection is very important in these smaller calibers. Of the 3 bullets I've tried on animals the only one I would use again is the 143 eldx.