If you hand load, it works about identical to the basic, not advanced, Hornady version Hilltop referred to. Has always got me close enough to start making a DOPE chart. If you are talking about using a program in the field at the time of the shot, I don't do that, but know some who do and use an app on their phone. Too many moving parts for me.
I'll cast another vote for the Hornady version I like the cheat sheet you can print. I'll laminate mine and tape it to the stock or some other highly visible location.
I use Ammoguide.com. I pay $17/yr., which I understand might rub a lot of guys the wrong way, but there is so much information on there it is worth it to me. I believe you can access a lot of the info without buying a membership though.
I am on the Hornady bandwagon. I printed out little sheets and taped them on the inside of my scope cover. On my muzzleloader, I have it taped to the butt-stock.
Applied ballistics or the shooter app can be downloaded on apple or android phones. Works fantastic. I'd recommend the shooter app as it is quite a bit cheaper than AP. I've taken many animals using both aps and they work extremely well