We all need to follow that philosophy and do as much as possible to always achieve humane kills! As CC mentioned, normally the best way to start out shooting with a new scope, a different bullet or load than you have been using. etc., is to shoot at a close distance to get fine tuned and then start stretching the distance out to see what kind of group you get at 100-200 yards or more. You shouldn't just rely on a ballistics table for stuff like that, but rather should shoot and practice out to whatever the furtherest distance you expect to be shooting on a hunt. IMHO you will normally want to have most centerfire rifles shooting from 1 1/2" to about 3" high at 100 yards if you will be hunting out west, as that will normally achieve a zero at around 200-225 yards. That allows a person to hold dead on an animal's vital zone out to at least 300 yards with no vertical compensation. That is how I have my .243, 25-06, and 2 of my 3 30-06s set that I take out to Wyoming where I may shoot out to around 300 yards or a little further. My sporterized 03A3 30-06 that I now have in a synthetic stock for use strictly in the lousy upper Mchigan November weather for whitetails is zeroed dead on at 100 yards because there are very few areas where I hunt up there where a shot further than that would be taken, so there is no need to have it shooting high at 100 yards.
Now with all the adjustable turret scopes available a person can just turn the elevation to a known range and rather than hold higher on an animal at a long distance like guys used to do you can hold the reticle right on the animal even though the rifle is aimed well above the target to drop the bullet into it. Of course, you now also have the lower priced scopes with reticles that have multiple stadia below the main reticle. Those are placed on the target at the known distance each of them is designed for using a particular load in that rifle/caliber. Things have come a long way from when I started shooting/hunting back in the early 50s. Some of it has been a positive and some IMHO has been a negative (LR hunting at extreme ranges where the animal has no chance, etc.) and I'll just leave it at that because we have already had a great thread on the latter!