I've been having a problem with deer being able to walk again after going down for a second. I hit my buck this year and his back legs gave out and he went down immediately. Then for whatever reason he learned to walk again and started limping down to the bottom of a draw. He got out of my sight and them popped up around a corner walking to me probably about 75 yards away when I put another one in it with a very hard quartering to angle if it wasn't straight on. This shot blew out the big hole in the stomach muscles but it didn't blow a full hole out of the skin. So it seemed to not do enough to the deer to kill it very quick but it also did a lot of damage. I might just try the Hornady 100 grns again if I can't find a box or a load for the E-tips and see if they do better this time.