It's hard to argue with success and it sounds like all who have replied have had success and believe in their bullet of choice. I don't think you can go wrong with any of the above mentioned choices I think it all depends on what your rifle shoots the best. My grandfather prefers Nosler Partition and won't hear of any other type. I used to use Core Lokt and the Nosler Partition with great success. After my trip to Africa I was sold on the Barnes Bullets because of there penetration capabilities, and where I live in California we have to use copper bullets. So my choice would be a 180 Grain TTSX Barnes Bullet. That's what I use in my 300 Weatherby.