Years ago when I first started the archery world I went back and forth on this. Embarrassed to say this but I lost a lot of animals. Probably 1 in 3. To the point that the bow was put away on the 5th day of a 135 day season with 7 unfilled tags in my pocket. Archery was dead to me. During the off season during discussions this topic came up a lot, but I knew this wasn't the solution. There were too many factors, as you archers are aware of, too list here. But here is what has brought me back. Type of broadhead... Nothing to do with it. Be accurate. My bow was at 70 lbs. I dropped it down to 58. Always wait for the PERFECT shot and know that a lot of animals will walk away from you at 20 yards. Whatever range you are comfortable shooting at with targets, reduce in the field. Before I pull the trigger, the animal has to be hit with the range finder, I know this may be a little extreme, but this is what I feel is the ethical route because of my experience. Now in 3 years not a single animal has been lost, usually 3-4 down a year.
So my opinion on broadheads... It doesn't matter. Accuracy, accuracy. find what you shoot well and know your effective range...in the field not your backyard.